Association Between FcγRIIa-R131 Allotype and Bacteremic Pneumococcal Pneumonia

Understanding mortality in bacteremic pneumococcal pneumonia.

Bacteremic pneumococcal pneumonia. A community hospital experience.

We reviewed our experience with bacteremic pneumococcal pneumonia (BPP) over a 1-year period at a 600-bed community teaching hospital; 26 cases were identified. The mean age was 57.5 years and there were 12 male and 14 female subjects. Cough, sputum production, fever, and mental status changes were the most frequent symptoms. Risk factors included drug abuse in 10, HIV in 4, current smoking in ...

Bacteremic pneumococcal pneumonia in HIV-seropositive and HIV-seronegative adults.

STUDY OBJECTIVES To compare the demographic, clinical, laboratory, and microbiological data, and the hospital course and outcome of HIV-seropositive and HIV-seronegative adults with bacteremic pneumococcal pneumonia. DESIGN Retrospective observation study conducted over a 2-year period. SETTING Academic teaching hospital attached to the University of the Witwatersrand, Johannesburg, South A...

Macrolide Resistance in Adults with Bacteremic Pneumococcal Pneumonia

We conducted a case-control study of adults with bacteremic pneumococcal pneumonia to identify factors associated with macrolide resistance. Study participants were identified through population-based surveillance in a 5-county region surrounding Philadelphia. Forty-three hospitals contributed 444 patients, who were interviewed by telephone regarding potential risk factors. In multivariable ana...

What is optimal antimicrobial therapy for bacteremic pneumococcal pneumonia?

Streptococcus pneumoniae is the leading cause of community-acquired pneumonia (CAP) and accounts for approximately two-thirds of cases of CAP associated with mortality [1]. The mortality rate associated with bacteremic pneumococcal pneumonia is 6%–20% [2]. Thus, bacteremic pneumococcal pneumonia has significant clinical importance, and any new information that may lead to better outcomes is wel...